Brief Information of the Compound and Protein
Compound Name
2-[[4-(5-chloropyrimidin-2-yl)piperazin-1-yl]methyl]-1-methylbenzimidazole
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PubChem ID
CID: 46190878
SID: 96044450
Canonical SMILES
Cn1c(CN2CCN(CC2)c2ncc(Cl)cn2)nc2ccccc12
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Compound Formula C17H19ClN6
Compound Structure
Protein Name
Metabotropic glutamate receptor 2
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
Q14416
Gene Name
GRM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
EC50 = 125.89 nM
   TI
   LI
   LO
   TS
2
EC50 = 1258.93 nM
   TI
   LI
   LO
   TS