Brief Information of the Compound and Protein
Compound Name
8-Fluoro-5-[2-(4-methoxyphenyl)ethyl]-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole
    Show/Hide
PubChem ID
CID: 46225027
Canonical SMILES
COc1ccc(CCn2c3CCN(C)Cc3c3cc(F)ccc23)cc1
    Show/Hide
Compound Formula C21H23FN2O
Compound Structure
Protein Name
Histamine H1 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Histamine receptor
Uniprot ID
P35367
Gene Name
HRH1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000289 SK-N-SH Homo sapiens (Human)  1
1
IC50 = 32 nM
   TI
   LI
   LO
   TS