Brief Information of the Compound and Protein
Compound Name
2,8-Dimethyl-5-phenethyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole
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PubChem ID
CID: 42631003
SID: 81069977
Canonical SMILES
CN1CCc2c(C1)c1cc(C)ccc1n2CCc1ccccc1
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Compound Formula C21H24N2
Compound Structure
Protein Name
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 158 nM
   TI
   LI
   LO
   TS
CL000017 HeLa Homo sapiens (Human)  1
1
Ki = 1.995 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 1.2 nM