Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(+/-)-8-(3-(5-fluoro-1H-indol-3-yl)propylamino)-2,3,8,9-tetrahydropyrano[3,2-e]isoindol-1(7H)-one
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 PubChem ID
CID: 16092107
SID: 24738282
Canonical SMILES
Fc1ccc2[nH]cc(CCCNC3COc4ccc5CNC(=O)c5c4C3)c2c1
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Compound Formula C22H22FN3O2
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 1A
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P08908
Gene Name
HTR1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
EC50 = 62 nM
   TI
   LI
   LO
   TS
2
Ki = 24 nM
   TI
   LI
   LO
   TS