Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine
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 PubChem ID
CID: 123631
SID: 14833109
Canonical SMILES
COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN1CCOCC1
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Compound Formula C22H24ClFN4O3
Compound Structure
Protein Name
 Protein Info 
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
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Primary active transporter
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ATP-binding cassette
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ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000756 MCF/MX
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 1100 nM
   TI
   LI
   LO
   TS
CL000031 MDCK
 Cell Line Info 
Canis lupus familiaris (Dog)  1
1
IC50 = 1260 nM
   TI
   LI
   LO
   TS
CL000036 MDCK-II
 Cell Line Info 
Canis lupus familiaris (Dog)  1
1
IC50 = 3190 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 400 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 300 nM