Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-{4-[2-Amino-6-(4-benzyl-piperazin-1-yl)-pyrimidin-4-yloxy]-phenyl}-2-methyl-2-phenoxy-propionic acid
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 PubChem ID
CID: 25227445
SID: 57578644
Canonical SMILES
CC(Cc1ccc(Oc2cc(nc(N)n2)N2CCN(Cc3ccccc3)CC2)cc1)(Oc1ccccc1)C(O)=O
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Compound Formula C31H33N5O4
Compound Structure
Protein Name
 Protein Info 
11-beta-hydroxysteroid dehydrogenase 1
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P50172
Gene Name
HSD11B1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 710 nM
   TI
   LI
   LO
   TS
2
Ki = 1000 nM
   TI
   LI
   LO
   TS