Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(16S,17R)-16-{[3-(dimethylamino)pyrrolidin-1-yl]carbonyl}-16,17-dihydroxy-4,14,19-triazaheptacyclo[12.11.2.0^{2,6}.0^{7,27}.0^{8,13}.0^{19,26}.0^{20,25}]heptacosa-1,6,8(13),9,11,20(25),21,23,26-nonaene-3,5-dione
    Show/Hide
 PubChem ID
CID: 45273361
Canonical SMILES
CN(C)C1CCN(C1)C(=O)[C@]1(O)Cn2c3ccccc3c3c4C(=O)NC(=O)c4c4c5ccccc5n(C[C@H]1O)c4c23
    Show/Hide
Compound Formula C31H29N5O5
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase JAK3
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
P52333
Gene Name
JAK3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 15 nM
   TI
   LI
   LO
   TS