Brief Information of the Compound and Protein
Compound Name
 Compound Info 
tert-butyl 4-[4-[1-(6-chloroimidazo[2,1-b][1,3]thiazol-5-yl)sulfonylpyrrolo[3,2-b]pyridin-6-yl]pyrazol-1-yl]piperidine-1-carboxylate
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 PubChem ID
CID: 45273344
Canonical SMILES
CC(C)(C)OC(=O)N1CCC(CC1)n1cc(cn1)-c1cnc2ccn(c2c1)S(=O)(=O)c1c(Cl)nc2sccn12
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Compound Formula C25H26ClN7O4S2
Compound Structure
Protein Name
 Protein Info 
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 450 nM
   TI
   LI
   LO
   TS
CL000413 MKN45
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 147 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 19 nM