Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-(6-(6-(4-methylpiperazin-1-yl)pyridin-3-yl)-1H-pyrrolo[3,2-b]pyridin-1-ylsulfonyl)benzo[c][1,2,5]oxadiazole
    Show/Hide
 PubChem ID
CID: 45270780
Canonical SMILES
CN1CCN(CC1)c1ccc(cn1)-c1cnc2ccn(c2c1)S(=O)(=O)c1cccc2nonc12
    Show/Hide
Compound Formula C23H21N7O3S
Compound Structure
Protein Name
 Protein Info 
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 1310 nM
   TI
   LI
   LO
   TS
CL000413 MKN45
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 820 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 15 nM