Brief Information of the Compound and Protein
Compound Name
1-(6-chloroimidazo[2,1-b]thiazol-5-ylsulfonyl)-1H-pyrrolo[3,2-b]pyridin-6-amine
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PubChem ID
CID: 45273339
Canonical SMILES
Nc1cnc2ccn(c2c1)S(=O)(=O)c1c(Cl)nc2sccn12
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Compound Formula C12H8ClN5O2S2
Compound Structure
Protein Name
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549 Homo sapiens (Human)  1
1
IC50 = 580 nM
   TI
   LI
   LO
   TS
CL000413 MKN45 Homo sapiens (Human)  1
1
IC50 = 490 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 10 nM