Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(+)-cis-Diltiazem
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 PubChem ID
CID: 39186
SID: 14929056
Canonical SMILES
COc1ccc(cc1)[C@@H]1Sc2ccccc2N(CCN(C)C)C(=O)[C@@H]1OC(C)=O
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Compound Formula C22H26N2O4S
Compound Structure
Protein Name
 Protein Info 
ATP-dependent translocase ABCB1
Protein Classification
Transporter
>
Primary active transporter
>
ATP-binding cassette
>
ABCB subfamily
Uniprot ID
P08183
Gene Name
ABCB1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000072 A2780
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 42657.95 nM
   TI
   LI
   LO
   TS
CL000135 A2780ADR
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 42657.95 nM
   TI
   LI
   LO
   TS
2
IC50 = 49000 nM
   TI
   LI
   LO
   TS
CL000009 LLC-PK1
 Cell Line Info 
Sus scrofa (Pig)  1
1
IC50 = 77700 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 61659.5 nM