Brief Information of the Compound and Protein
Compound Name
(4aS,8aR)-4-(3,4-dimethoxyphenyl)-2-[[4-[(4-oxopiperidin-1-yl)methyl]phenyl]methyl]-4a,5,8,8a-tetrahydrophthalazin-1-one
    Show/Hide
PubChem ID
CID: 12000858
SID: 17500115
Canonical SMILES
COc1ccc(cc1OC)C1=NN(Cc2ccc(CN3CCC(=O)CC3)cc2)C(=O)[C@@H]2CC=CC[C@H]12
    Show/Hide
Compound Formula C29H33N3O4
Compound Structure
Protein Name
3',5'-cyclic-AMP phosphodiesterase 4D
Protein Classification
Enzyme
>
Phosphodiesterase
>
Phosphodiesterase 4
>
Phosphodiesterase 4D
Uniprot ID
Q08499
Gene Name
PDE4D
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000018 HL-60 Homo sapiens (Human)  1
1
IC50 = 0.9 nM
   TI
   LI
   LO
   TS