Brief Information of the Compound and Protein
Compound Name
6-[(1,1-Dioxidoisothiazolidin-2-yl)methyl]-5-[4-(ethylsulfonyl)phenoxy]-2-(pyridin-2-yl)-1H-benzimidazole
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PubChem ID
CID: 11649204
SID: 16752586
Canonical SMILES
CCS(=O)(=O)c1ccc(Oc2cc3[nH]c(nc3cc2CN2CCCS2(=O)=O)-c2ccccn2)cc1
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Compound Formula C24H24N4O5S2
Compound Structure
Protein Name
Hexokinase-4
Protein Classification
Enzyme
Uniprot ID
P35557
Gene Name
GCK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
EC50 = 90 nM
   TI
   LI
   LO
   TS
2
EC50 = 460 nM
   TI
   LI
   LO
   TS