Bioactivity Information

Brief Information of the Compound and Protein

Compound Name

Compound Info

C18130

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PubChem ID

CID: 5480230

SID: 14937121

Canonical SMILES	Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1[nH]c2[C@@H]4Oc6c7c(C[C@H]8N(CC9CC9)CC[C@@]47[C@@]8(O)Cc2c1C[C@@]35O)ccc6O Show/Hide
Compound Formula	C40H43N3O6

Compound Structure

Protein Name

Protein Info

Delta-type opioid receptor

Protein Classification

Membrane receptor

Family A G protein-coupled receptor

Peptide receptor (family A GPCR)

Short peptide receptor (family A GPCR)

Opioid receptor

Uniprot ID

P41143

Gene Name

OPRD1

Table of Molecular Bioactivities Related to the Compound and Protein

Cell-based Assay

Cell Line ID	Cell Line Name	Cell Line Organism
CL000011	CHO Cell Line Info	Cricetulus griseus (Chinese hamster)	7
1	EC50 = 380 nM	TI LI LO TS
2	Ki = 5.07 nM	TI LI LO TS
3	Ki = 5.7 nM	TI LI LO TS
4	Ki = 19 nM	TI LI LO TS
5	Ki = 19.5 nM	TI LI LO TS
6	Ki = 24 nM	TI LI LO TS
7	Ki = 65.2 nM	TI LI LO TS
CL000006	HEK293 Cell Line Info	Homo sapiens (Human)	4
1	IC50 = 24 nM	TI LI LO TS
2	Ki = 0.3 nM	TI LI LO TS
3	Ki = 0.8 nM	TI LI LO TS
4	Ki = 6.56 nM	TI LI LO TS

Biochemical Assays

1	Ki = 5.7 nM
2	Ki = 43 nM