Brief Information of the Compound and Protein
Compound Name
(2R)-1-[3-Chloro-4-({(2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methylpiperazin-1-yl}sulfonyl)phenyl]-N,N-dimethylpiperidin-4-amine
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PubChem ID
CID: 44247843
SID: 85281536
Canonical SMILES
C[C@@H]1CN(CCN1S(=O)(=O)c1ccc(cc1Cl)N1CCC(CC1)N(C)C)c1ccc(F)cc1C(F)(F)F
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Compound Formula C25H31ClF4N4O2S
Compound Structure
Protein Name
11-beta-hydroxysteroid dehydrogenase 1
Protein Classification
Enzyme
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Oxidoreductase
Uniprot ID
P28845
Gene Name
HSD11B1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 15 nM
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