Brief Information of the Compound and Protein
Compound Name
2-[1-[1-(4-fluoro-2-methylphenyl)-2,3-dihydropyrrolo[2,3-b]pyridin-4-yl]pyrazol-3-yl]-1,3-thiazole
    Show/Hide
PubChem ID
CID: 44589206
Canonical SMILES
Cc1cc(F)ccc1N1CCc2c1nccc2-n1ccc(n1)-c1nccs1
    Show/Hide
Compound Formula C20H16FN5S
Compound Structure
Protein Name
Corticotropin-releasing factor receptor 1
Protein Classification
Membrane receptor
>
Family B G protein-coupled receptor
>
Peptide receptor (family B GPCR)
>
Corticotropin releasing factor receptor
>
Corticotropin releasing factor receptor
Uniprot ID
P34998
Gene Name
CRHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 162.18 nM
   TI
   LI
   LO
   TS