Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[1-[3-[2,4-bis(trifluoromethyl)phenyl]-2,5-dimethylimidazo[4,5-b]pyridin-7-yl]pyrazol-3-yl]-1,3-thiazole
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 PubChem ID
CID: 25149344
SID: 56481522
Canonical SMILES
Cc1nc2c(cc(C)nc2n1-c1ccc(cc1C(F)(F)F)C(F)(F)F)-n1ccc(n1)-c1nccs1
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Compound Formula C22H14F6N6S
Compound Structure
Protein Name
 Protein Info 
Corticotropin-releasing factor receptor 1
Protein Classification
Membrane receptor
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Family B G protein-coupled receptor
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Peptide receptor (family B GPCR)
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Corticotropin releasing factor receptor
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Corticotropin releasing factor receptor
Uniprot ID
P34998
Gene Name
CRHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS