Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-[2,4-bis(trifluoromethyl)phenyl]-5-methyl-7-[3-(1,3-thiazol-2-yl)pyrazol-1-yl]-1H-imidazo[4,5-b]pyridin-2-one
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 PubChem ID
CID: 25150450
SID: 56482699
Canonical SMILES
Cc1cc(-n2ccc(n2)-c2nccs2)c2[nH]c(=O)n(-c3ccc(cc3C(F)(F)F)C(F)(F)F)c2n1
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Compound Formula C21H12F6N6OS
Compound Structure
Protein Name
 Protein Info 
Corticotropin-releasing factor receptor 1
Protein Classification
Membrane receptor
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Family B G protein-coupled receptor
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Peptide receptor (family B GPCR)
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Corticotropin releasing factor receptor
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Corticotropin releasing factor receptor
Uniprot ID
P34998
Gene Name
CRHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 8317.64 nM
   TI
   LI
   LO
   TS