Brief Information of the Compound and Protein
Compound Name
4-[4-[3-(1,3-thiazol-2-yl)pyrazol-1-yl]-2,3-dihydropyrrolo[2,3-b]pyridin-1-yl]benzene-1,3-dicarbonitrile
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PubChem ID
CID: 44589258
Canonical SMILES
N#Cc1ccc(N2CCc3c2nccc3-n2ccc(n2)-c2nccs2)c(c1)C#N
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Compound Formula C21H13N7S
Compound Structure
Protein Name
Corticotropin-releasing factor receptor 1
Protein Classification
Membrane receptor
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Family B G protein-coupled receptor
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Peptide receptor (family B GPCR)
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Corticotropin releasing factor receptor
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Corticotropin releasing factor receptor
Uniprot ID
P34998
Gene Name
CRHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 7413.1 nM
   TI
   LI
   LO
   TS