Brief Information of the Compound and Protein
Compound Name
(rel)-(8-(bis(2-chlorophenyl)methyl)-3-(pyridin-2-yl)-8-aza-bicyclo[3.2.1]octan-3-yl)-N,N-dimethylmethanamine
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Canonical SMILES
CN(C)C[C@@]1(c2ccccn2)C[C@H]2CC[C@@H](C1)N2C(c1ccccc1Cl)c1ccccc1Cl
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Compound Formula C28H31Cl2N3
Compound Structure
Protein Name
Nociceptin receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Opioid receptor
Uniprot ID
P41146
Gene Name
OPRL1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
EC50 = 156 nM
   TI
   LI
   LO
   TS
2
Ki = 7 nM
   TI
   LI
   LO
   TS