Brief Information of the Compound and Protein
Compound Name
(S)-2-((4-(1H-Indol-3-yl)-5,6-dihydropyridin-1(2H)-yl)-methyl)-8-methyl-2,3-dihydro-[1,4]dioxino-[2,3-f]quinoline
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PubChem ID
CID: 9866320
SID: 15224323
Canonical SMILES
Cc1ccc2c3O[C@@H](CN4CCC(=CC4)c4c[nH]c5ccccc45)COc3ccc2n1
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Compound Formula C26H25N3O2
Compound Structure
Protein Name
5-hydroxytryptamine receptor 1A
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P08908
Gene Name
HTR1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
IC50 = 56.7 nM
   TI
   LI
   LO
   TS
2
Ki = 3.02 nM
   TI
   LI
   LO
   TS