Brief Information of the Compound and Protein
Compound Name
 Compound Info 
CAS_136434-34-9
    Show/Hide
 PubChem ID
CID: 60835
SID: 14873633
Canonical SMILES
CNCC[C@H](Oc1cccc2ccccc12)c1cccs1
    Show/Hide
Compound Formula C18H19NOS
Compound Structure
Protein Name
 Protein Info 
Sodium-dependent dopamine transporter
Protein Classification
Transporter
>
Electrochemical transporter
>
SLC superfamily of solute carriers
>
SLC06 neurotransmitter transporter family
Uniprot ID
Q01959
Gene Name
SLC6A3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  7
1
IC50 = 590 nM
   TI
   LI
   LO
   TS
2
IC50 = 660 nM
   TI
   LI
   LO
   TS
3
IC50 = 870 nM
   TI
   LI
   LO
   TS
4
IC50 = 977 nM
   TI
   LI
   LO
   TS
5
Ki = 316.23 nM
   TI
   LI
   LO
   TS
6
Ki = 435 nM
   TI
   LI
   LO
   TS
7
Ki = 484 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 660 nM
2 Ki = 240 nM
3 Ki = 251.19 nM
4 Ki = 370 nM