Brief Information of the Compound and Protein
Compound Name
1-(2-(6-(3-Amino-2-oxo-1,2-dihydroquinoxalin-5-yloxy)pyrimidin-4-yl)-5-(trifluoromethyl)phenyl)-3-tert-butylurea
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PubChem ID
CID: 24858172
SID: 50089122
Canonical SMILES
CC(C)(C)NC(=O)Nc1cc(ccc1-c1cc(Oc2cccc3[nH]c(=O)c(N)nc23)ncn1)C(F)(F)F
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Compound Formula C24H22F3N7O3
Compound Structure
Protein Name
Transient receptor potential cation channel subfamily V member 1
Protein Classification
Ion channel
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Voltage-gated ion channel
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Transient receptor potential channel
Uniprot ID
O35433
Gene Name
TRPV1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
IC50 = 4.1 nM
   TI
   LI
   LO
   TS
2
IC50 = 5.2 nM
   TI
   LI
   LO
   TS