Brief Information of the Compound and Protein
Compound Name
3-Amino-5-(6-(2-(2-morpholinoethylamino)-6-(trifluoromethyl)pyridin-3-yl)pyrimidin-4-yloxy)quinoxalin-2(1H)-one
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PubChem ID
CID: 24858482
SID: 50089446
Canonical SMILES
Nc1nc2c(Oc3cc(ncn3)-c3ccc(nc3NCCN3CCOCC3)C(F)(F)F)cccc2[nH]c1=O
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Compound Formula C24H23F3N8O3
Compound Structure
Protein Name
Transient receptor potential cation channel subfamily V member 1
Protein Classification
Ion channel
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Voltage-gated ion channel
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Transient receptor potential channel
Uniprot ID
O35433
Gene Name
TRPV1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
IC50 = 2.2 nM
   TI
   LI
   LO
   TS
2
IC50 = 18.8 nM
   TI
   LI
   LO
   TS