Brief Information of the Compound and Protein
Compound Name
3-Amino-5-(2-(1-(pyridin-2-yl)ethylamino)-6-(4-(trifluoromethyl)-phenyl)pyrimidin-4-yloxy)quinoxalin-2(1H)-one
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PubChem ID
CID: 24860064
SID: 50091217
Canonical SMILES
CC(Nc1nc(Oc2cccc3[nH]c(=O)c(N)nc23)cc(n1)-c1ccc(cc1)C(F)(F)F)c1ccccn1
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Compound Formula C26H20F3N7O2
Compound Structure
Protein Name
Transient receptor potential cation channel subfamily V member 1
Protein Classification
Ion channel
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Voltage-gated ion channel
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Transient receptor potential channel
Uniprot ID
O35433
Gene Name
TRPV1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
IC50 = 2.8 nM
   TI
   LI
   LO
   TS
2
IC50 = 5.7 nM
   TI
   LI
   LO
   TS