Brief Information of the Compound and Protein
Compound Name
3-amino-5-(6-(2-amino-6-(trifluoromethyl)pyridin-3-yl)-2-((S)-1-methoxypropan-2-ylamino)pyrimidin-4-yloxy)quinoxalin-2(1H)-one
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PubChem ID
CID: 11511709
SID: 16613606
Canonical SMILES
COC[C@H](C)Nc1nc(Oc2cccc3[nH]c(=O)c(N)nc23)cc(n1)-c1ccc(nc1N)C(F)(F)F
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Compound Formula C22H21F3N8O3
Compound Structure
Protein Name
Transient receptor potential cation channel subfamily V member 1
Protein Classification
Ion channel
>
Voltage-gated ion channel
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Transient receptor potential channel
Uniprot ID
O35433
Gene Name
TRPV1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
IC50 = 4.4 nM
   TI
   LI
   LO
   TS
2
IC50 = 6.4 nM
   TI
   LI
   LO
   TS