Brief Information of the Compound and Protein
Compound Name
3-(pyrido[2,3-d]pyrimidin-2-yl)benzonitrile
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PubChem ID
CID: 44435038
Canonical SMILES
N#Cc1cccc(c1)-c1ncc2cccnc2n1
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Compound Formula C14H8N4
Compound Structure
Protein Name
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P31424
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 > 26100 nM
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