Brief Information of the Compound and Protein
Compound Name
3-(6-chloro-imidazo[2,1-b]thiazole-5-sulfonyl)-1-(1-ethyl-pyrrolidin-3-yl)-1H-pyrrolo[2,3-b]pyridine
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PubChem ID
CID: 44433195
Canonical SMILES
CCN1CCC(n2cc(S(=O)(=O)C3=C(Cl)NC4SC=CN34)c3cccnc32)C1
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Compound Formula C18H20ClN5O2S2
Compound Structure
Protein Name
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  2
1
IC50 = 10 nM
   TI
   LI
   LO
   TS
2
Ki = 1.4 nM
   TI
   LI
   LO
   TS