Brief Information of the Compound and Protein
Compound Name
1-(1-ethylpiperidin-3-yl)-3-(phenylsulfonyl)-1Hpyrrolo[2,3-b]pyridine
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PubChem ID
CID: 11545169
SID: 16647357
Canonical SMILES
CCN1CCCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1ccccc1
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Compound Formula C20H23N3O2S
Compound Structure
Protein Name
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  2
1
IC50 = 26 nM
   TI
   LI
   LO
   TS
2
Ki = 3.6 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 3.631 nM