Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-(2-methylquinolin-7-yl)-5-(trifluoromethoxy)benzonitrile
    Show/Hide
 PubChem ID
CID: 44432684
Canonical SMILES
Cc1ccc2ccc(cc2n1)-c1cc(OC(F)(F)F)cc(c1)C#N
    Show/Hide
Compound Formula C18H11F3N2O
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
>
Small molecule receptor (family C GPCR)
>
Neurotransmitter receptor (family C GPCR)
>
Metabotropic glutamate receptor
Uniprot ID
P31424
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 75 nM
   TI
   LI
   LO
   TS