Brief Information of the Compound and Protein
Compound Name
3-[(2-methyl-4-thiazolyl)ethynyl]-5-vinylpyridine
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PubChem ID
CID: 11608287
SID: 16711062
Canonical SMILES
Cc1nc(cs1)C#Cc1cncc(C=C)c1
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Compound Formula C13H10N2S
Compound Structure
Protein Name
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 2.01 nM
   TI
   LI
   LO
   TS
CL000058 T-REx-293 Homo sapiens (Human)  1
1
Ki = 1.003 nM
   TI
   LI
   LO
   TS