Brief Information of the Compound and Protein
Compound Name
4-(3,5-difluorophenylethynyl)-2-methylthiazole
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PubChem ID
CID: 11543200
SID: 16645328
Canonical SMILES
Cc1nc(cs1)C#Cc1cc(F)cc(F)c1
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Compound Formula C12H7F2NS
Compound Structure
Protein Name
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 25.3 nM
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   LI
   LO
   TS