Brief Information of the Compound and Protein
Compound Name
3-[(2,5-dimethyl-4-thiazolyl)ethynyl]pyridine
    Show/Hide
PubChem ID
CID: 11615445
SID: 16718287
Canonical SMILES
Cc1nc(C#Cc2cccnc2)c(C)s1
    Show/Hide
Compound Formula C12H10N2S
Compound Structure
Protein Name
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
>
Small molecule receptor (family C GPCR)
>
Neurotransmitter receptor (family C GPCR)
>
Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 698 nM
   TI
   LI
   LO
   TS