Brief Information of the Compound and Protein
Compound Name
(2S)-2-hydroxy-3-phenyl-N-(3-spiro[1,2-dihydroindene-3,4'-piperidine]-1'-ylpropyl)propanamide
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PubChem ID
CID: 11633324
SID: 16743017
Canonical SMILES
O[C@@H](Cc1ccccc1)C(=O)NCCCN1CCC2(CCc3ccccc23)CC1
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Compound Formula C25H32N2O2
Compound Structure
Protein Name
Nociceptin receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Opioid receptor
Uniprot ID
P41146
Gene Name
OPRL1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  3
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
2
IC50 = 7.5 nM
   TI
   LI
   LO
   TS
3
IC50 = 12 nM
   TI
   LI
   LO
   TS