Brief Information of the Compound and Protein
Compound Name
 Compound Info 
12'-bromo-4'-[4-(difluoromethoxy)phenyl]-1-methyl-8'-oxa-5',6'-diazaspiro[piperidine-4,7'-tricyclo[7.4.0.0^{2,6}]tridecane]-1'(13'),4',9',11'-tetraene
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 PubChem ID
CID: 3716424
Canonical SMILES
CN1CCC2(CC1)Oc1ccc(Br)cc1C1CC(=NN21)c1ccc(OC(F)F)cc1
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Compound Formula C22H22BrF2N3O2
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 2B
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P41595
Gene Name
HTR2B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 175 nM
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