Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(E)-3-{3-[3,5-Di-tert-butyl-2-(2,2-difluoro-ethoxy)-phenyl]-1H-indol-5-yl}-but-2-enoic acid
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 PubChem ID
CID: 10298831
SID: 15305532
Canonical SMILES
C\C(=C/C(O)=O)c1ccc2[nH]cc(-c3cc(cc(c3OCC(F)F)C(C)(C)C)C(C)(C)C)c2c1
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Compound Formula C28H33F2NO3
Compound Structure
Protein Name
 Protein Info 
Retinoic acid receptor RXR-alpha
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 2
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Nuclear hormone receptor subfamily 2 group B
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Nuclear hormone receptor subfamily 2 group B member 1
Uniprot ID
P19793
Gene Name
RXRA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000044 CV-1
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  3
1
EC50 = 65 nM
   TI
   LI
   LO
   TS
2
EC50 = 66.3 nM
   TI
   LI
   LO
   TS
3
Ki = 1.6 nM
   TI
   LI
   LO
   TS