Brief Information of the Compound and Protein
Compound Name
7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one
    Show/Hide
PubChem ID
CID: 60795
SID: 15103350
Canonical SMILES
Clc1cccc(N2CCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl
    Show/Hide
Compound Formula C23H27Cl2N3O2
Compound Structure
Protein Name
5-hydroxytryptamine receptor 2B
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P41595
Gene Name
HTR2B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 1.259 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 1.4 nM
2 Ki = 5.6 nM