Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-cyclohexyl-1-[4-[2-(1H-imidazol-2-yl)ethylamino]phenyl]-3,8-dimethyl-1,3,4-benzotriazepin-2-one
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 PubChem ID
CID: 23626557
SID: 46487256
Canonical SMILES
CN1N=C(C2CCCCC2)c2ccc(C)cc2N(c2ccc(NCCc3ncc[nH]3)cc2)C1=O
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Compound Formula C27H32N6O
Compound Structure
Protein Name
 Protein Info 
Parathyroid hormone/parathyroid hormone-related peptide receptor
Protein Classification
Membrane receptor
>
Family B G protein-coupled receptor
>
Peptide receptor (family B GPCR)
>
Parathyroid hormone receptor
>
Parathyroid hormone receptor
Uniprot ID
Q03431
Gene Name
PTH1R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Kd = 2884.03 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
Kd = 16.98 nM
   TI
   LI
   LO
   TS
2
Ki = 13.18 nM
   TI
   LI
   LO
   TS
CL000099 SaOS-2
 Cell Line Info 
Homo sapiens (Human)  1
1
Kd = 19.5 nM
   TI
   LI
   LO
   TS