Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(18Z)-12-methoxy-3,5,5-trimethyl-18-({3-[(2E)-pent-2-en-2-yl]thiophen-2-yl}methylidene)-17-oxa-6-azatetracyclo[8.8.0.0^{2,7}.0^{11,16}]octadeca-1(10),2(7),3,8,11,13,15-heptaen-13-ol
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 PubChem ID
CID: 17758236
SID: 29219158
Canonical SMILES
CC\C=C(/C)c1ccsc1\C=C1/Oc2ccc(O)c(OC)c2-c2ccc3NC(C)(C)C=C(C)c3c12
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Compound Formula C30H31NO3S
Compound Structure
Protein Name
 Protein Info 
Glucocorticoid receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
>
Nuclear hormone receptor subfamily 3 group C member 1
Uniprot ID
P04150
Gene Name
NR3C1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000044 CV-1
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  1
1
EC50 = 0.5 nM
   TI
   LI
   LO
   TS
CL000186 RPMI-8226
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 6.1 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 4.4 nM