Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US8748608, 20
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 PubChem ID
CID: 44427835
Canonical SMILES
CC(=O)OC(CCNC(=O)c1ccc(cc1)-c1ccccn1)CN1CCN(CC1)c1cccc(Cl)c1Cl
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Compound Formula C28H30Cl2N4O3
Compound Structure
Protein Name
 Protein Info 
D(3) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P35462
Gene Name
DRD3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  3
1
EC50 = 3.9 nM
   TI
   LI
   LO
   TS
2
IC50 = 5.4 nM
   TI
   LI
   LO
   TS
3
Ki = 11.7 nM
   TI
   LI
   LO
   TS