Brief Information of the Compound and Protein
Compound Name
2-{[4,8-bis(butylamino)-6-[(2-hydroxyethyl)amino]pyrimido[5,4-d][1,3]diazin-2-yl]amino}ethan-1-ol
    Show/Hide
PubChem ID
CID: 16757482
SID: 26746468
Canonical SMILES
CCCCNc1nc(NCCO)nc2c(NCCCC)nc(NCCO)nc12
    Show/Hide
Compound Formula C18H32N8O2
Compound Structure
Protein Name
Equilibrative nucleoside transporter 1
Protein Classification
Transporter
>
Electrochemical transporter
>
SLC superfamily of solute carriers
>
SLC28 and SLC29 families of nucleoside transporters
>
SLC29 Facilitative nucleoside transporter family
Uniprot ID
Q99808
Gene Name
SLC29A1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000002 K-562 Homo sapiens (Human)  2
1
IC50 = 8655 nM
   TI
   LI
   LO
   TS
2
Ki = 489 nM
   TI
   LI
   LO
   TS