Brief Information of the Compound and Protein
Compound Name
2-{[4,8-bis({8-azabicyclo[3.2.1]octan-8-yl})-6-[bis(2-hydroxyethyl)amino]pyrimido[5,4-d][1,3]diazin-2-yl](2-hydroxyethyl)amino}ethan-1-ol
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PubChem ID
CID: 24860453
Canonical SMILES
OCCN(CCO)c1nc(N2C3CCC2CCC3)c2nc(nc(N3C4CCC3CCC4)c2n1)N(CCO)CCO
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Compound Formula C28H44N8O4
Compound Structure
Protein Name
Equilibrative nucleoside transporter 1
Protein Classification
Transporter
>
Electrochemical transporter
>
SLC superfamily of solute carriers
>
SLC28 and SLC29 families of nucleoside transporters
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SLC29 Facilitative nucleoside transporter family
Uniprot ID
Q99808
Gene Name
SLC29A1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000002 K-562 Homo sapiens (Human)  2
1
IC50 = 3416 nM
   TI
   LI
   LO
   TS
2
Ki = 193 nM
   TI
   LI
   LO
   TS