Brief Information of the Compound and Protein
Compound Name
(2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-{[(4-nitrophenyl)methyl]sulfanyl}-9H-purin-9-yl)oxolane-3,4-diol
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PubChem ID
CID: 65407
SID: 14758167
Canonical SMILES
OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(SCc3ccc(cc3)[N+]([O-])=O)ncnc12
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Compound Formula C17H17N5O6S
Compound Structure
Protein Name
Equilibrative nucleoside transporter 1
Protein Classification
Transporter
>
Electrochemical transporter
>
SLC superfamily of solute carriers
>
SLC28 and SLC29 families of nucleoside transporters
>
SLC29 Facilitative nucleoside transporter family
Uniprot ID
Q99808
Gene Name
SLC29A1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000002 K-562 Homo sapiens (Human)  3
1
IC50 = 7.6 nM
   TI
   LI
   LO
   TS
2
Ki = 0.43 nM
   TI
   LI
   LO
   TS
3
Ki = 0.7 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.3 nM
2 IC50 = 8.511 nM
3 Ki = 0.7 nM
4 Ki = 0.7079 nM