Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-(2-(methyl(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)amino)pyrimidin-5-yl)acetic acid
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 PubChem ID
CID: 11576047
SID: 16678397
Canonical SMILES
CCCc1c(OCCCN(C)c2ncc(CC(O)=O)cn2)ccc2c(noc12)C(F)(F)F
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Compound Formula C21H23F3N4O4
Compound Structure
Protein Name
 Protein Info 
Oxysterols receptor LXR-beta
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group H
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Nuclear hormone receptor subfamily 1 group H member 3
Uniprot ID
P55055
Gene Name
NR1H2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 470 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 55 nM