Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-oxo-1-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)indoline-5-carboxylic acid
    Show/Hide
 PubChem ID
CID: 11655575
SID: 16759089
Canonical SMILES
CCCc1c(OCCCN2C(=O)Cc3cc(ccc23)C(O)=O)ccc2c(noc12)C(F)(F)F
    Show/Hide
Compound Formula C23H21F3N2O5
Compound Structure
Protein Name
 Protein Info 
Oxysterols receptor LXR-beta
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 1
>
Nuclear hormone receptor subfamily 1 group H
>
Nuclear hormone receptor subfamily 1 group H member 3
Uniprot ID
P55055
Gene Name
NR1H2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 4400 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 700 nM