Brief Information of the Compound and Protein
Compound Name
(R)-(6-(4-(4-(benzylamino)-6-(trifluoromethyl)-1H-benzo[d]-imidazol-2-yl)-3-methylpiperazin-1-yl)-5-chloropyridin-3-yl)-methanol
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PubChem ID
CID: 11548261
SID: 16650406
Canonical SMILES
C[C@@H]1CN(CCN1c1nc2c(NCc3ccccc3)cc(cc2[nH]1)C(F)(F)F)c1ncc(CO)cc1Cl
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Compound Formula C26H26ClF3N6O
Compound Structure
Protein Name
Transient receptor potential cation channel subfamily V member 1
Protein Classification
Ion channel
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Voltage-gated ion channel
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Transient receptor potential channel
Uniprot ID
O35433
Gene Name
TRPV1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
IC50 = 6.7 nM
   TI
   LI
   LO
   TS
2
IC50 = 7 nM
   TI
   LI
   LO
   TS