Brief Information of the Compound and Protein
Compound Name
6-(trifluoromethyl)-2-[4-[3-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]-N-[(3,4,5-trifluorophenyl)methyl]-1H-benzimidazol-4-amine
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PubChem ID
CID: 11541493
SID: 16643552
Canonical SMILES
Fc1cc(CNc2cc(cc3[nH]c(nc23)N2CCN(CC2)c2ncccc2C(F)(F)F)C(F)(F)F)cc(F)c1F
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Compound Formula C25H19F9N6
Compound Structure
Protein Name
Transient receptor potential cation channel subfamily V member 1
Protein Classification
Ion channel
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Voltage-gated ion channel
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Transient receptor potential channel
Uniprot ID
O35433
Gene Name
TRPV1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
IC50 = 81 nM
   TI
   LI
   LO
   TS
2
IC50 = 132 nM
   TI
   LI
   LO
   TS