Brief Information of the Compound and Protein
Compound Name
6-(trifluoromethyl)-N-[[4-(trifluoromethyl)phenyl]methyl]-2-[4-[3-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]-1H-benzimidazol-5-amine
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PubChem ID
CID: 9985817
SID: 14963830
Canonical SMILES
FC(F)(F)c1ccc(CNc2cc3[nH]c(nc3cc2C(F)(F)F)N2CCN(CC2)c2ncccc2C(F)(F)F)cc1
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Compound Formula C26H21F9N6
Compound Structure
Protein Name
Transient receptor potential cation channel subfamily V member 1
Protein Classification
Ion channel
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Voltage-gated ion channel
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Transient receptor potential channel
Uniprot ID
O35433
Gene Name
TRPV1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
IC50 = 94 nM
   TI
   LI
   LO
   TS
2
IC50 = 141 nM
   TI
   LI
   LO
   TS