Brief Information of the Compound and Protein
Compound Name
(R)-2-(4-(5-bromo-3-chloropyridin-2-yl)-2-methylpiperazin-1-yl)-6-(trifluoromethyl)-4-(3,4,5-trifluorophenyl)-1H-benzo[d]-imidazole
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PubChem ID
CID: 11498102
SID: 16599954
Canonical SMILES
C[C@@H]1CN(CCN1c1nc2c(cc(cc2[nH]1)C(F)(F)F)-c1cc(F)c(F)c(F)c1)c1ncc(Br)cc1Cl
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Compound Formula C24H17BrClF6N5
Compound Structure
Protein Name
Transient receptor potential cation channel subfamily V member 1
Protein Classification
Ion channel
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Voltage-gated ion channel
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Transient receptor potential channel
Uniprot ID
O35433
Gene Name
TRPV1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
IC50 = 3.3 nM
   TI
   LI
   LO
   TS
2
IC50 = 3.4 nM
   TI
   LI
   LO
   TS