Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-benzyl-3-[2-(4-methylanilino)-5-nitrophenyl]sulfonylurea
    Show/Hide
 PubChem ID
CID: 11568384
SID: 16670663
Canonical SMILES
Cc1ccc(Nc2ccc(cc2S(=O)(=O)NC(=O)NCc2ccccc2)[N+]([O-])=O)cc1
    Show/Hide
Compound Formula C21H20N4O5S
Compound Structure
Protein Name
 Protein Info 
Thromboxane A2 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
>
Prostanoid receptor
Uniprot ID
P21731
Gene Name
TBXA2R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000053 COS-7
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  2
1
IC50 = 1.17 nM
   TI
   LI
   LO
   TS
2
IC50 = 1.9 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 45.01 nM
   TI
   LI
   LO
   TS
2
IC50 = 64.47 nM
   TI
   LI
   LO
   TS